منابع مشابه
β-endorphin neuron transplantation
We summarize here our new discovery that the endogenous opioid peptide β-endorphin (BEP), by virtue of reducing body stress and maintaining active immune system, as well as, balancing the levels of pro-inflammatory and anti-inflammatory cytokines, destroys tumor cells and stops them from being transformed into metastatic cancer cells.
متن کاملRegulation of cancer progression by β-endorphin neuron.
It is becoming increasingly clear that stressful life events can affect cancer growth and metastasis by modulating nervous, endocrine, and immune systems. The purpose of this review is to briefly describe the process by which stress may potentiate carcinogenesis and how reducing body stress may prevent cancer growth and progression. The opioid peptide β-endorphin plays a critical role in bringi...
متن کاملRegulation of Cancer Progression by b-Endorphin Neuron
It is becoming increasingly clear that stressful life events can affect cancer growth andmetastasis by modulating nervous, endocrine, and immunesystems.Thepurposeof this review is tobrieflydescribe theprocess bywhich stress may potentiate carcinogenesis and how reducing body stress may prevent cancer growth and progression. The opioid peptide b-endorphin plays a critical role in bringing the st...
متن کاملSkin β-Endorphin Mediates Addiction to UV Light
UV light is an established carcinogen, yet evidence suggests that UV-seeking behavior has addictive features. Following UV exposure, epidermal keratinocytes synthesize proopiomelanocortin (POMC) that is processed to melanocyte-stimulating hormone, inducing tanning. We show that, in rodents, another POMC-derived peptide, β-endorphin, is coordinately synthesized in skin, elevating plasma levels a...
متن کاملβ-endorphin degradation and the individual reactivity to traumatic stress.
Reactivity to traumatic stress varies between individuals and only a minority of those exposed to trauma develops stress-induced psychopathologies. Currently extensive effort is made to unravel the specific mechanisms predisposing to vulnerability vs. resilience to stress. We investigated in rats the role of β-endorphin metabolism in vulnerability to acute traumatic stress. Responders (showing ...
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ژورنال
عنوان ژورنال: OncoImmunology
سال: 2012
ISSN: 2162-402X
DOI: 10.4161/onci.19335